Peginterferon Alfa-2a in Patients with Chronic Hepatitis C and Cirrhosis

Abstract

In patients with chronic hepatitis C and cirrhosis or bridging fibrosis, 180 microg of peginterferon alfa-2a administered once weekly is significantly more effective than 3 million units of standard interferon alfa-2a administered three times weekly.

Keywords

MedicineCirrhosisGastroenterologyInternal medicineRegimenChronic hepatitisInterferonPeginterferon alfa-2aHepatitis CInterferon alfaAlpha interferonRibavirinImmunologyVirus

MeSH Terms

Antiviral AgentsDrug Administration ScheduleFemaleHepacivirusHepatitis CChronicHumansInjectionsSubcutaneousInterferon alpha-2Interferon-alphaLiver CirrhosisMaleMiddle AgedPolyethylene GlycolsRNAViralRecombinant Proteins

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Publication Info

Year: 2000
Type: article
Volume: 343
Issue: 23
Pages: 1673-1680
Citations: 885
Access: Closed

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APA Style

                            
                                
                                    E. Jenny Heathcote, 
                                
                                    Mitchell L. Shiffman, 
                                
                                    W. Graham E. Cooksley
                                
                                et al.
                            
                            (2000). 
                            Peginterferon Alfa-2a in Patients with Chronic Hepatitis C and Cirrhosis. 
                            New England Journal of Medicine
                            , 343
                            (23)
                            , 1673-1680.
                            https://doi.org/10.1056/nejm200012073432302
                        

Identifiers

DOI: 10.1056/nejm200012073432302
PMID: 11106716

Data Quality

Data completeness: 86%