Pembrolizumab for Early Triple-Negative Breast Cancer

2020 New England Journal of Medicine 2,718 citations

Abstract

Among patients with early triple-negative breast cancer, the percentage with a pathological complete response was significantly higher among those who received pembrolizumab plus neoadjuvant chemotherapy than among those who received placebo plus neoadjuvant chemotherapy. (Funded by Merck Sharp & Dohme [a subsidiary of Merck]; KEYNOTE-522 ClinicalTrials.gov number, NCT03036488.).

Keywords

PembrolizumabTriple-negative breast cancerMedicineBreast cancerOncologyInternal medicineChemotherapyCancerPathologicalComplete responseImmunotherapy

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Publication Info

Year
2020
Type
article
Volume
382
Issue
9
Pages
810-821
Citations
2718
Access
Closed

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Peter Schmid, Javier Cortés, Lajos Pusztai et al. (2020). Pembrolizumab for Early Triple-Negative Breast Cancer. New England Journal of Medicine , 382 (9) , 810-821. https://doi.org/10.1056/nejmoa1910549

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DOI
10.1056/nejmoa1910549