Percutaneous Repair or Medical Treatment for Secondary Mitral Regurgitation

2018 New England Journal of Medicine 1,654 citations

Abstract

Among patients with severe secondary mitral regurgitation, the rate of death or unplanned hospitalization for heart failure at 1 year did not differ significantly between patients who underwent percutaneous mitral-valve repair in addition to receiving medical therapy and those who received medical therapy alone. (Funded by the French Ministry of Health and Research National Program and Abbott Vascular; MITRA-FR ClinicalTrials.gov number, NCT01920698 .).

Keywords

MedicineEjection fractionHazard ratioMitral regurgitationHeart failureCardiologyInternal medicineOdds ratioMitral valveConfidence intervalPercutaneousSurgeryMitral valve repair

MeSH Terms

AgedAged80 and overCombined Modality TherapyFemaleHeart FailureHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHospitalizationHumansIntention to Treat AnalysisKaplan-Meier EstimateMaleMiddle AgedMitral ValveMitral Valve InsufficiencyPercutaneous Coronary InterventionProsthesis FailureStroke VolumeTreatment OutcomeVentricular DysfunctionLeft

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Publication Info

Year
2018
Type
article
Volume
379
Issue
24
Pages
2297-2306
Citations
1654
Access
Closed

Social Impact

Social media, news, blog, policy document mentions

Citation Metrics

1654
OpenAlex
75
Influential
1505
CrossRef

Cite This

Jean‐François Obadia, David Messika‐Zeitoun, Guillaume Leurent et al. (2018). Percutaneous Repair or Medical Treatment for Secondary Mitral Regurgitation. New England Journal of Medicine , 379 (24) , 2297-2306. https://doi.org/10.1056/nejmoa1805374

Identifiers

DOI
10.1056/nejmoa1805374
PMID
30145927

Data Quality

Data completeness: 90%