Abstract
AZD6140 100 and 200 mg bid were well tolerated and were superior to AZD6140 50 mg bid and clopidogrel 75 mg qd with regard to antiplatelet efficacy.
Keywords
ClopidogrelMedicineAspirinPharmacodynamicsP2Y12PharmacokineticsLoading doseDosingPlateletAntagonistPharmacologyAnesthesiaCrossover studyPlatelet aggregation inhibitorInternal medicinePlaceboReceptor
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Publication Info
- Year
- 2006
- Type
- article
- Volume
- 27
- Issue
- 9
- Pages
- 1038-1047
- Citations
- 734
- Access
- Closed
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Cite This
Steen Husted,
Håkan Emanuelsson,
Stan Heptinstall
et al.
(2006).
Pharmacodynamics, pharmacokinetics, and safety of the oral reversible P2Y12 antagonist AZD6140 with aspirin in patients with atherosclerosis: a double-blind comparison to clopidogrel with aspirin.
European Heart Journal
, 27
(9)
, 1038-1047.
https://doi.org/10.1093/eurheartj/ehi754
Identifiers
- DOI
- 10.1093/eurheartj/ehi754