Keywords
Protein kinase BComputational biologyProto-Oncogene Proteins c-aktRelevance (law)BiologyPI3K/AKT/mTOR pathwayCell biologySignal transductionPolitical science
Affiliated Institutions
Related Publications
The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.
Serum and certain growth factors have the ability to inhibit programmed cell death (apoptosis) and promote survival. The mechanism by which growth factors deliver an anti-apopto...
mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs
Proliferation Control The protein complex mTORC1, which contains the protein kinase known as mammalian target of rapamycin, is an important regulator of cell proliferation and c...
Phosphorylation of the Translational Repressor PHAS-I by the Mammalian Target of Rapamycin
The immunosuppressant rapamycin interferes with G 1 -phase progression in lymphoid and other cell types by inhibiting the function of the mammalian target of rapamycin (mTOR). m...
The Phosphoinositide 3-Kinase Pathway
Phosphorylated lipids are produced at cellular membranes during signaling events and contribute to the recruitment and activation of various signaling components. The role of ph...
Publication Info
- Year
- 2001
- Type
- review
- Volume
- 2
- Issue
- 10
- Pages
- 760-768
- Citations
- 609
- Access
- Closed
External Links
Social Impact
Altmetric
PlumX Metrics
Social media, news, blog, policy document mentions
Citation Metrics
609
OpenAlex
Cite This
Michael P. Scheid,
James R. Woodgett
(2001).
PKB/AKT: functional insights from genetic models.
Nature Reviews Molecular Cell Biology
, 2
(10)
, 760-768.
https://doi.org/10.1038/35096067
Identifiers
- DOI
- 10.1038/35096067