Abstract

Defense cargo shuttles in vesicles Plants can use small RNAs (sRNAs) to interfere with virulence factor gene expression in pathogens. Cai et al. show that the small mustard plant Arabidopsis shuttles defensive sRNAs into the necrotrophic fungus Botrytis cinerea via extracellular vesicles (see the Perspective by Thomma and Cook). The vesicles are associated with tetraspanin proteins, which can interact and form membrane microdomains. Several dozen different sRNAs targeting the pathogenic process were transported from Arabidopsis to B. cinerea in a selective manner. Science , this issue p. 1126 ; see also p. 1070

Keywords

ArabidopsisBiologyVirulenceBotrytis cinereaGeneVesicleCell biologyFungusTetraspaninGene expressionVirulence factorExtracellularMicrobiologyBotanyMutantGeneticsCellMembrane

Affiliated Institutions

Related Publications

Publication Info

Year
2018
Type
article
Volume
360
Issue
6393
Pages
1126-1129
Citations
1115
Access
Closed

External Links

View on DOI.org

Social Impact

Altmetric
PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

1115
OpenAlex

Cite This

Qiang Cai, Lulu Qiao, Ming Wang et al. (2018). Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes. Science , 360 (6393) , 1126-1129. https://doi.org/10.1126/science.aar4142

Identifiers

DOI
10.1126/science.aar4142