Abstract
Prescribing medication for children requires extra caution compared to prescribing in adults as there are differences in pharmacokinetics in different age groups affecting the pharmacodynamics of drugs. There is a lack of new drug development trials in children due to ethical concerns about conducting trials and about recruitment. This leads to prescribing medication which is off-label or unlicensed and this needs to be explained to parents and children to gain informed consent and answer any queries. Palatability of a medicine plays a big role and can raise challenges for parents during administration. Techniques to aid administration such as masking the taste, using an oral syringe or giving a strongly flavoured food or drink after administration of medicine may be helpful.
Affiliated Institutions
Related Publications
En Route to Ethical Recommendations for Gene Transfer Clinical Trials
In Geneva, Switzerland, on 2–3 April 2007, Clinigene-NoE (the European Network for the Advancement of Clinical Gene Transfer and Therapy) and Consert (program on Concerted Safet...
Family pediatrics: report of the Task Force on the Family.
WHY A TASK FORCE ON THE FAMILY? The practice of pediatrics is unique among medical specialties in many ways, among which is the nearly certain presence of a parent when health c...
Randomised controlled trials – the gold standard for effectiveness research
RCTs are prospective studies that measure the effectiveness of interventions. Although no study is likely on its own to prove causality, randomisation reduces bias and provides ...
Publication Info
- Year
- 2025
- Type
- article
- Citations
- 0
- Access
- Closed
External Links
Social Impact
Social media, news, blog, policy document mentions
Citation Metrics
Cite This
Identifiers
- DOI
- 10.1177/17557380251400210