Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens

Fiona M. Behan; Francesco Iorio; Gabriele Picco; Emanuel Gonçalves; Charlotte Beaver; Giorgia Migliardi; Rita Santos; Yanhua Rao; Francesco Sassi; Marika Pinnelli; Rizwan Ansari; Sarah Harper; David A. Jackson; Rebecca McRae; Rachel Pooley; Piers Wilkinson; Dieudonne van der Meer; David J. Dow; Carolyn Buser‐Doepner; Andrea Bertotti; Livio Trusolino; Euan A. Stronach; Julio Sáez-Rodríguez; Kosuke Yusa; Mathew J. Garnett

doi:10.1038/s41586-019-1103-9

Keywords

CRISPRComputational biologyCancerDrug discoveryPrioritizationDrug developmentIdentification (biology)Cancer cell linesCas9BiologyGenomicsCancer cellGenomeComputer scienceBioinformaticsDrugGeneticsGenePharmacology

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Publication Info

Year: 2019
Type: article
Volume: 568
Issue: 7753
Pages: 511-516
Citations: 1305
Access: Closed

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APA Style

                            
                                
                                    Fiona M. Behan, 
                                
                                    Francesco Iorio, 
                                
                                    Gabriele Picco
                                
                                et al.
                            
                            (2019). 
                            Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens. 
                            Nature
                            , 568
                            (7753)
                            , 511-516.
                            https://doi.org/10.1038/s41586-019-1103-9
                        

Identifiers

DOI: 10.1038/s41586-019-1103-9