Keywords
Affiliated Institutions
Related Publications
Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains
Insulators are DNA elements that prevent inappropriate interactions between the neighboring regions of the genome. They can be functionally classified as either enhancer blocker...
A machine learning framework for the prediction of chromatin folding in <i>Drosophila</i> using epigenetic features
Technological advances have lead to the creation of large epigenetic datasets, including information about DNA binding proteins and DNA spatial structure. Hi-C experiments have ...
Rapid, low-input, low-bias construction of shotgun fragment libraries by high-density in vitro transposition
Abstract We characterize and extend a highly efficient method for constructing shotgun fragment libraries in which transposase catalyzes in vitro DNA fragmentation and adaptor i...
Waves of Retrotransposon Expansion Remodel Genome Organization and CTCF Binding in Multiple Mammalian Lineages
CTCF-binding locations represent regulatory sequences that are highly constrained over the course of evolution. To gain insight into how these DNA elements are conserved and spr...
Publication Info
- Year
- 2011
- Type
- article
- Volume
- 43
- Issue
- 11
- Pages
- 1059-1065
- Citations
- 633
- Access
- Closed
External Links
Social Impact
Social media, news, blog, policy document mentions
Citation Metrics
Cite This
Identifiers
- DOI
- 10.1038/ng.947