Psilocybin in Alcohol Use Disorder Maintains Abstinence Efficacy: A Scoping Review

Abstract

Alcohol use disorder is a psychiatric condition characterized by excessive alcohol consumption. The drugs that are used to treat it often fail to prevent relapse. At the same time, psilocybin is increasingly being investigated for the treatment of various substance use disorders. This review aims to evaluate the results of the most recent clinical trials assessing psilocybin as a treatment for alcohol use disorder. According to these trials, psilocybin seems to reduce craving but its effect on overall alcohol consumption is less clear. There is no doubt that future trials would benefit from larger sample sizes and standardized tests.

Affiliated Institutions

• École Normale Supérieure BI
• Centre National de la Recherche Scientifique FR
• Centre de Biophysique Moléculaire FR
• Hôpital Paul-Brousse FR
• Université d'Orléans FR

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