Abstract
Affective disturbances are a common consequence of organic brain lesions of varying aetiology, and it is to be expected that the differentiation between affective symptoms of “functional” origin and those resulting from organic lesions would become an increasingly difficult problem in an age-range which is particularly susceptible to pathological cerebral changes. In fact the classical accounts of mental disorder in old age convey the impression, by their emphasis on the depressive form of senile psychosis, that an affective disorder appearing in senescence is commonly the manifestation of some cerebral degenerative process. This is one of the sources of the widely prevalent view in contemporary clinical practice that there is a large group of cases in which dementia and a depressive (and less often a manic) symptom-complex are associated. The overlap being large, an ill-defined line of demarcation is held to exist in old age between the organic degenerative diseases and the affective illnesses of a “functional” kind.
Keywords
MeSH Terms
Affiliated Institutions
Related Publications
The Association Between Quantitative Measures of Dementia and of Senile Change in the Cerebral Grey Matter of Elderly Subjects
The ageing of many populations in recent years has directed increasing attention to the social, medical and biological problems of senescence. The psychological changes associat...
The Stages of Mania
The progression of symptoms during an acute manic episode was studied retrospectively in 20 bipolar manic-depressive patients whose diagnosis was reconfirmed at follow-up. Three...
Clinical-Neuropathological Correlations in Alzheimer's Disease and Related Dementias
Clinicians accurately predicted AD pathological findings or their absence in most cases. Attributing other degenerative dementias to AD, misdiagnosing patients with combined AD ...
The Global Deterioration Scale for assessment of primary degenerative dementia
Cognitive decline associated with old age and consistent with the diagnosis of primary degenerative dementia is a unique clinical syndrome with characteristic phenomena and prog...
Depressive mood and obesity in US adults: comparison and moderation by sex, age, and race
Sustained depressive mood is a gateway symptom for a major depressive disorder. This paper investigated whether the association between depressive mood and obesity differs as fu...
Publication Info
- Year
- 1953
- Type
- article
- Volume
- 99
- Issue
- 416
- Pages
- 439-450
- Citations
- 101
- Access
- Closed
External Links
Social Impact
Social media, news, blog, policy document mentions
Citation Metrics
Cite This
Identifiers
- DOI
- 10.1192/bjp.99.416.439
- PMID
- 13069989