Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension

Keywords

MedicineBlood pressurePlaceboEnalaprilStroke (engine)SittingHydrochlorothiazideDiastoleInternal medicineCardiologyClinical endpointSystolic hypertensionSurgeryAnesthesiaRandomized controlled trialAngiotensin-converting enzyme

Affiliated Institutions

Related Publications

Impact of Age on the Importance of Systolic and Diastolic Blood Pressures for Stroke Risk

Julie K.K. Vishram , Anders Borglykke , Anne Helms Andreasen +13 more

This study investigates age-related shifts in the relative importance of systolic (SBP) and diastolic (DBP) blood pressures as predictors of stroke and whether these relations a...

2012 Hypertension 115 citations

Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies

M R Law , Joan K. Morris , Nicholas Wald

With the exception of the extra protective effect of beta blockers given shortly after a myocardial infarction and the minor additional effect of calcium channel blockers in pre...

2009 BMJ 2727 citations

Effect of Antihypertensive Treatment in Patients Having Already Suffered From Stroke

François Gueyffier , Jean‐Pierre Boissel , Florent Boutitie +10 more

Background and Purpose Drug treatment of high blood pressure has been shown to reduce the associated cardiovascular risk. Stroke represents the type of event more strongly linke...

1997 Stroke 247 citations

Blood Pressure Parameters and Risk of Fatal Stroke, NHANES II Mortality Study

Devin L. Brown , Warwick Giles , Kurt J. Greenlund

Our results agree with previous studies that indicate systolic BP is an important predictor of stroke risk for all groups within the population and provide further evidence of t...

2007 American Journal of Hypertension 97 citations

Effects of blood pressure lowering on outcome incidence in hypertension. 1. Overview, meta-analyses, and meta-regression analyses of randomized trials

Costas Thomopoulos , Gianfranco Parati , Alberto Zanchetti

Meta-analyses of all BP-lowering RCTs involving hypertensive patients provide precise estimates of benefits (larger for stroke and heart failure, but also significant for CHD an...

2014 Journal of Hypertension 364 citations

Publication Info

Year: 1997
Type: article
Volume: 350
Issue: 9080
Pages: 757-764
Citations: 2992
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

2992

OpenAlex

Cite This

APA Style

                            
                                
                                    Jan A. Staessen, 
                                
                                    Robert Fagard, 
                                
                                    Lutgarde Thijs
                                
                                et al.
                            
                            (1997). 
                            Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. 
                            The Lancet
                            , 350
                            (9080)
                            , 757-764.
                            https://doi.org/10.1016/s0140-6736(97)05381-6
                        

Identifiers

DOI: 10.1016/s0140-6736(97)05381-6