Relation of cognitive activity to risk of developing Alzheimer disease

R. J. Wilson; Paul A. Scherr; Julie A. Schneider; Y. Tang; David A. Bennett

doi:10.1212/01.wnl.0000271087.67782.cb

Abstract

Level of cognitively stimulating activity in old age is related to risk of developing dementia.

Keywords

CognitionDementiaNeuropathologyMedicineSocioeconomic statusAlzheimer's diseaseIncidence (geometry)Cognitive declineDiseaseEffects of sleep deprivation on cognitive performanceGerontologyPsychologyInternal medicinePsychiatryPopulationEnvironmental health

Affiliated Institutions

Related Publications

Cognitive activity and the cognitive morbidity of Alzheimer disease

Robert S. Wilson , Lisa L. Barnes , Neelum T. Aggarwal +4 more

Mentally stimulating activity in old age appears to compress the cognitive morbidity associated with AD by slowing cognitive decline before dementia onset and hastening it there...

2010 Neurology 124 citations

Mild cognitive impairment

C.A. Luis , David Loewenstein , Amarilis Acevedo +2 more

Mild cognitive impairment (MCI), an intermediate state between normal aging and dementia, is characterized by acquired cognitive deficits, without significant decline in functio...

2003 Neurology 243 citations

The changing prevalence and incidence of dementia over time — current evidence

Yu‐Tzu Wu , Alexa S. Beiser , Monique M.B. Breteler +15 more

Dementia is an increasing focus for policymakers, civil organizations and multidisciplinary researchers. The most recent descriptive epidemiological research into dementia is en...

2017 Nature Reviews Neurology 739 citations

Diabetes Mellitus and Risk of Alzheimer Disease and Decline in Cognitive Function

Zoe Arvanitakis , R. J. Wilson , Julia L. Bienias +2 more

Diabetes mellitus may be associated with an increased risk of developing AD and may affect cognitive systems differentially.

2004 Archives of Neurology 1242 citations

Longitudinal assessment of Aβ and cognition in aging and Alzheimer disease

Victor L. Villemagne , Kerryn E. Pike , Gaël Chételat +14 more

Abstract Objective Assess Aβ deposition longitudinally and explore its relationship with cognition and disease progression. Methods Clinical follow‐up was obtained 20 ± 3 months...

2011 Annals of Neurology 801 citations

Publication Info

Year: 2007
Type: article
Volume: 69
Issue: 20
Pages: 1911-1920
Citations: 379
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Relation of cognitive activity to risk of developing Alzheimer disease

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

379

OpenAlex

Cite This

APA Style

                            
                                
                                    R. J. Wilson, 
                                
                                    Paul A. Scherr, 
                                
                                    Julie A. Schneider
                                
                                et al.
                            
                            (2007). 
                            Relation of cognitive activity to risk of developing Alzheimer disease. 
                            Neurology
                            , 69
                            (20)
                            , 1911-1920.
                            https://doi.org/10.1212/01.wnl.0000271087.67782.cb
                        

Identifiers

DOI: 10.1212/01.wnl.0000271087.67782.cb