Reversal of multidrug resistance by transferrin-conjugated liposomes co-encapsulating doxorubicin and verapamil.

Jun Wu; Yanhui Lu; Alice Lee; Xiaogang Pan; Xiao‐Juan Yang; Xiaobin Zhao; Robert J. Lee

Abstract

The combination of TfR targeting and co-encapsulation of DOX and VER was highly effective in overcoming drug resistance in K562 leukemia cells.

Keywords

LiposomeDoxorubicinCytotoxicityChemistryMTT assayPharmacologyDaunorubicinMultiple drug resistanceIn vitroBiochemistryMedicineChemotherapyLeukemiaImmunology

Affiliated Institutions

The Ohio State University US

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Publication Info

Year: 2007
Type: article
Volume: 10
Issue: 3
Pages: 350-7
Citations: 172
Access: Closed

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APA Style

                            
                                    Jun Wu, 
                                
                                    Yanhui Lu, 
                                
                                    Alice Lee
                                
                                et al.
                            
                            (2007). 
                            Reversal of multidrug resistance by transferrin-conjugated liposomes co-encapsulating doxorubicin and verapamil.. 
                            PubMed
                            , 10
                            (3)
                            , 350-7.