Abstract

Since the 1990 NIH-sponsored conference on polycystic ovary syndrome (PCOS), it has become appreciated that the syndrome encompasses a broader spectrum of signs and symptoms of ovarian dysfunction than those defined by the original diagnostic criteria. The 2003 Rotterdam consensus workshop concluded that PCOS is a syndrome of ovarian dysfunction along with the cardinal features hyperandrogenism and polycystic ovary (PCO) morphology. PCOS remains a syndrome and, as such, no single diagnostic criterion (such as hyperandrogenism or PCO) is sufficient for clinical diagnosis. Its clinical manifestations may include: menstrual irregularities, signs of androgen excess, and obesity. Insulin resistance and elevated serum LH levels are also common features in PCOS. PCOS is associated with an increased risk of type 2 diabetes and cardiovascular events.

Keywords

Polycystic ovaryHyperandrogenismInsulin resistanceMedicineAndrogen ExcessGynecologyOvaryObesityInternal medicineEndocrinology

MeSH Terms

Clinical Trials as TopicConsensus Development Conferences as TopicConsensus Development ConferencesNIH as TopicFemaleHumansHyperandrogenismInsulin ResistanceLuteinizing HormonePolycystic Ovary SyndromeRisk FactorsUnited States

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Publication Info

Year
2004
Type
article
Volume
81
Issue
1
Pages
19-25
Citations
8865
Access
Closed

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Cite This

Chang J, Bouchard, P., Diamanti, E et al. (2004). Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertility and Sterility , 81 (1) , 19-25. https://doi.org/10.1016/j.fertnstert.2003.10.004

Identifiers

DOI
10.1016/j.fertnstert.2003.10.004
PMID
14688154

Data Quality

Data completeness: 86%