Rewiring central metabolism in Komagataella phaffii for efficient mannose synthesis

Sijia Zhao; Yuheng Wang; Lianjun Song; Jiachen Xie; Xinxin Xu; Wei Zhang; Jie Zhang; Bo Liu

doi:10.1186/s12934-025-02886-8

Abstract

This study achieved efficient mannose production in K. phaffii by remodeling central metabolism. It not only offers a new route for mannose biosynthesis but also establishes a model framework for engineering K. phaffii to produce other high-value bioactive compounds.

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Publication Info

Year: 2025
Type: article
Citations: 0
Access: Closed

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APA Style

                            
                                    Sijia Zhao, 
                                
                                    Yuheng Wang, 
                                
                                    Lianjun Song
                                
                                et al.
                            
                            (2025). 
                            Rewiring central metabolism in Komagataella phaffii for efficient mannose synthesis. 
                            Microbial Cell Factories
                            
                            .
                            https://doi.org/10.1186/s12934-025-02886-8

Identifiers

DOI: 10.1186/s12934-025-02886-8