Rfam 11.0: 10 years of RNA families | RDL Research Database

Abstract

The Rfam database (available via the website at http://rfam.sanger.ac.uk and through our mirror at http://rfam.janelia.org) is a collection of non-coding RNA families, primarily RNAs with a conserved RNA secondary structure, including both RNA genes and mRNA cis-regulatory elements. Each family is represented by a multiple sequence alignment, predicted secondary structure and covariance model. Here we discuss updates to the database in the latest release, Rfam 11.0, including the introduction of genome-based alignments for large families, the introduction of the Rfam Biomart as well as other user interface improvements. Rfam is available under the Creative Commons Zero license.

Keywords

BiologyComputational biologyRNAAngiogeninGeneticsGene

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Publication Info

Year: 2012
Type: article
Volume: 41
Issue: D1
Pages: D226-D232
Citations: 832
Access: Closed

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APA Style

                            
                                
                                    Sarah Burge, 
                                
                                    Jennifer Daub, 
                                
                                    Ruth Y. Eberhardt
                                
                                et al.
                            
                            (2012). 
                            Rfam 11.0: 10 years of RNA families. 
                            Nucleic Acids Research
                            , 41
                            (D1)
                            , D226-D232.
                            https://doi.org/10.1093/nar/gks1005
                        

Identifiers

DOI: 10.1093/nar/gks1005