Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

Abstract

A two-dose regimen of BNT162b2 conferred 95% protection against Covid-19 in persons 16 years of age or older. Safety over a median of 2 months was similar to that of other viral vaccines. (Funded by BioNTech and Pfizer; ClinicalTrials.gov number, NCT04368728.).

Keywords

Coronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakVirologyBusinessMedicineOutbreakInternal medicineInfectious disease (medical specialty)

MeSH Terms

AdolescentAdultAgedBNT162 VaccineCOVID-19COVID-19 VaccinesFatigueFemaleHeadacheHumansImmunizationSecondaryMaleMiddle AgedSARS-CoV-2Single-Blind MethodTreatment OutcomeVaccinesSyntheticYoung AdultmRNA Vaccines

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Publication Info

Year: 2020
Type: article
Volume: 383
Issue: 27
Pages: 2603-2615
Citations: 14917
Access: Closed

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APA Style

                            
                                
                                    Fernando P. Polack, 
                                
                                    Stephen J. Thomas, 
                                
                                    Nicholas Kitchin
                                
                                et al.
                            
                            (2020). 
                            Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine. 
                            New England Journal of Medicine
                            , 383
                            (27)
                            , 2603-2615.
                            https://doi.org/10.1056/nejmoa2034577
                        

Identifiers

DOI: 10.1056/nejmoa2034577
PMID: 33301246
PMCID: PMC7745181

Data Quality

Data completeness: 90%