Abstract

Aetiology confronts two distinct issues: the determinants of individual cases, and the determinants of incidence rate. If exposure to a necessary agent is homogeneous within a population, then case/control and cohort methods will fail to detect it: they will only identify markers of susceptibility. The corresponding strategies in control are the 'high-risk' approach, which seeks to protect susceptible individuals, and the population approach, which seeks to control the causes of incidence. The two approaches are not usually in competition, but the prior concern should always be to discover and control the causes of incidence.

Keywords

EpidemiologyDiseaseSick leaveMedicineEthosFamily medicinePsychologyPathology

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Publication Info

Year
1985
Type
article
Volume
14
Issue
1
Pages
32-38
Citations
2588
Access
Closed

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Geoffrey Rose (1985). Sick Individuals and Sick Populations. International Journal of Epidemiology , 14 (1) , 32-38. https://doi.org/10.1093/ije/14.1.32

Identifiers

DOI
10.1093/ije/14.1.32