Abstract

This report demonstrates that a rapid decrease of peripheral T cell subsets is a unique characteristic in patients with SARS during acute infection, although total white blood cell counts, red blood cell counts, and platelet counts remain relatively normal. In recovering patients, a rapid and dramatic restoration of peripheral T cell subsets was seen in the periphery. Although the underlying mechanism of the acute decrease of peripheral T cell subsets observed in patients with SARS during the acute stage remains unknown, this clinical characteristic can facilitate an earlier and more accurate diagnosis of SARS.

Keywords

PeripheralPeripheral bloodMedicineSevere acute respiratory syndromeLymphocyte subsetsWhite blood cellRespiratory systemPlateletImmunologyCellT cellPeripheral blood cellInternal medicineImmune systemBiologyCoronavirus disease 2019 (COVID-19)Disease

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Year
2004
Type
article
Volume
189
Issue
4
Pages
648-651
Citations
290
Access
Closed

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Taisheng Li, Zhifeng Qiu, Linqi Zhang et al. (2004). Significant Changes of Peripheral T Lymphocyte Subsets in Patients with Severe Acute Respiratory Syndrome. The Journal of Infectious Diseases , 189 (4) , 648-651. https://doi.org/10.1086/381535

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DOI
10.1086/381535