Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis

Arun C. Habermann; Austin J. Gutierrez; Linh T. Bui; Stephanie L. Yahn; Nichelle I. Winters; Carla L. Calvi; Lance Peter; Mei-I Chung; Chase J. Taylor; Christopher S. Jetter; Latha Raju; Jamie Roberson; Guixiao Ding; Lori Wood; Jennifer M. S. Sucre; Bradley W. Richmond; Ana Serezani; Wyatt J. McDonnell; S. Mallal; Matthew J. Bacchetta; James E. Loyd; Ciara M. Shaver; Lorraine B. Ware; Ross M. Bremner; Rajat Walia; Timothy S. Blackwell; Nicholas E. Banovich; Jonathan A. Kropski

doi:10.1126/sciadv.aba1972

Abstract

Single-cell RNA sequencing provides new insights into pathologic epithelial and mesenchymal remodeling in the human lung.

Keywords

Mesenchymal stem cellRNABiologyCellPulmonary fibrosisLungFibrosisCell biologyPathologyGeneGeneticsMedicineInternal medicine

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Publication Info

Year: 2020
Type: article
Volume: 6
Issue: 28
Citations: 980
Access: Closed

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APA Style

                            
                                
                                    Arun C. Habermann, 
                                
                                    Austin J. Gutierrez, 
                                
                                    Linh T. Bui
                                
                                et al.
                            
                            (2020). 
                            Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis. 
                            Science Advances
                            , 6
                            (28)
                            .
                            https://doi.org/10.1126/sciadv.aba1972
                        

Identifiers

DOI: 10.1126/sciadv.aba1972