Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia

Oliver Rausch; Konstantinos Tzelepis; Tony Kouzarides; Eliza Yankova; Wesley Blackaby; Mark R. Albertella; Justyna Rak; Étienne De Braekeleer; Georgia Tsagkogeorga; Ewa S. Pilka; Demetrios Aspris; Dan Leggate; Alan G. Hendrick; Natalie Webster; Byron Andrews; Richard Fosbeary; Patrick Guest; Nerea Irigoyen; Maria Eleftheriou; Malgorzata Gozdecka; João M.L. Dias; Andrew J. Bannister; Binje Vick; Irmela Jeremias; George S. Vassiliou

doi:10.1038/s41586-021-03536-w

Keywords

Cancer researchMethyltransferaseIn vivoRNAMyeloid leukemiaBiologyChemistryCell biologyBiochemistryGeneGenetics

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Publication Info

Year: 2021
Type: article
Volume: 593
Issue: 7860
Pages: 597-601
Citations: 1169
Access: Closed

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APA Style

                            
                                
                                    Oliver Rausch, 
                                
                                    Konstantinos Tzelepis, 
                                
                                    Tony Kouzarides
                                
                                et al.
                            
                            (2021). 
                            Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia. 
                            Nature
                            , 593
                            (7860)
                            , 597-601.
                            https://doi.org/10.1038/s41586-021-03536-w
                        

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DOI: 10.1038/s41586-021-03536-w