Keywords
microRNABiologyGenePiwi-interacting RNAGermlineComputational biologyRegulation of gene expressionGeneticsGene expressionNon-coding RNARNALong non-coding RNARNA interference
Affiliated Institutions
Related Publications
Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation
MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating gene expression. The majority of miRNAs are transcribed from DNA sequences into primary...
Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing
Dicer is the enzyme that cleaves double-stranded RNA (dsRNA) into 21–25-nt-long species responsible for sequence-specific RNA-induced gene silencing at the transcriptional, post...
MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias
Little is known about the expression levels or function of micro-RNAs (miRNAs) in normal and neoplastic cells, although it is becoming clear that miRNAs play important roles in ...
Inducible MicroRNA-223 Down-Regulation Promotes TLR-Triggered IL-6 and IL-1β Production in Macrophages by Targeting STAT3
MicroRNAs are small non-coding RNA molecules that regulate gene expression by either translational inhibition or mRNA degradation. MicroRNAs play pivotal roles in the regulation...
Publication Info
- Year
- 2008
- Type
- review
- Volume
- 9
- Issue
- 3
- Pages
- 219-230
- Citations
- 1358
- Access
- Closed
External Links
Social Impact
Altmetric
PlumX Metrics
Social media, news, blog, policy document mentions
Citation Metrics
1358
OpenAlex
Cite This
Giovanni Stefani,
Frank J. Slack
(2008).
Small non-coding RNAs in animal development.
Nature Reviews Molecular Cell Biology
, 9
(3)
, 219-230.
https://doi.org/10.1038/nrm2347
Identifiers
- DOI
- 10.1038/nrm2347