Abstract

We performed MRI of brain and spinal cord on 80 patients with multiple sclerosis (MS). Using multi-array coils and fast spin echo, 139 intrinsic lesions were identified in 59 patients (74%). Lesions were more common in the cervical than in the thoracic cord. Cross-sectional areas of the cord, measured from axial images at four levels, showed atrophy in 40%. Clinical disability correlated with cord atrophy but not with cord lesion load. These results show that the use of multi-array coils and fast spin echo allows rapid and sensitive detection of spinal cord lesions in MS and that the cord is involved in the majority of patients. A lack of association between cord lesions and disability may relate to limitations in MR resolution but also suggests that the mechanisms of disability in MS are complex and multifactorial.

Keywords

Spinal cordMultiple sclerosisCordMedicineAtrophyMagnetic resonance imagingLesionSpin echoRadiologyPathologySurgery

MeSH Terms

AdultBrainHumansMagnetic Resonance ImagingMultiple SclerosisNeckRecurrenceSpinal CordThorax

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Publication Info

Year
1993
Type
article
Volume
43
Issue
12
Pages
2632-2632
Citations
342
Access
Closed

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Cite This

Desmond P. Kidd, J. W. Thorpe, Alan J. Thompson et al. (1993). Spinal cord MRI using multi‐array coils and fast spin echo. Neurology , 43 (12) , 2632-2632. https://doi.org/10.1212/wnl.43.12.2632

Identifiers

DOI
10.1212/wnl.43.12.2632
PMID
8255468

Data Quality

Data completeness: 81%