Abstract

<h3>Abstract</h3> Here we demonstrate the Argo System, a massively parallel neural recording system based on platinum-iridium microwire electrode arrays bonded to a CMOS voltage amplifier array. The Argo system is the highest channel count in vivo neural recording system built to date, supporting simultaneous recording from 65,536 channels, sampled at over 32 kHz and 12-bit resolution. This system is designed for cortical recordings, compatible with both penetrating and surface microelectrodes. We have validated this system by recording spiking activity from 791 neurons in rats and cortical surface Local Field Potential (LFP) activity from over 30,000 channels in sheep. While currently adapted for head-fixed recording, the microwire-CMOS architecture is well suited for clinical translation. Thus, this demonstration helps pave the way for a future high data rate intracortical implant.

Keywords

Multielectrode arrayMicroelectrodeCMOSAmplifierComputer scienceArgoLocal field potentialElectrode arrayMassively parallelField-programmable gate arrayComputer hardwareVoltageElectrodeElectronic engineeringElectrical engineeringNeurosciencePhysicsEngineeringBiologyGeology

MeSH Terms

Analysis of VarianceRegression AnalysisStatistics as Topic

Affiliated Institutions

Related Publications

Publication Info

Year
1994
Type
article
Volume
308
Issue
6933
Pages
896-896
Citations
226
Access
Closed

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Citation Metrics

226
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2
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196
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Cite This

Martin Bland, Doug Altman (1994). Statistics Notes: Correlation, regression, and repeated data. BMJ , 308 (6933) , 896-896. https://doi.org/10.1136/bmj.308.6933.896

Identifiers

DOI
10.1136/bmj.308.6933.896
PMID
8173371
PMCID
PMC2539813

Data Quality

Data completeness: 86%