Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor

Thomas G. Davies; Johanne Bentley; Christine E. Arris; F. Thomas Boyle; Nicola J. Curtin; Jane Endicott; Ashleigh E. Gibson; Bernard T. Golding; Roger J. Griffin; Ian R. Hardcastle; Philip J. Jewsbury; L.N. Johnson; Véronique Mesguiche; David R. Newell; M.E.M. Noble; Julie A. Tucker; Lan Wang; Hayley J. Whitfield

doi:10.1038/nsb842

Keywords

Cyclin-dependent kinaseCyclin-dependent kinase 2Cyclin-dependent kinase 1ChemistryKinaseCDK inhibitorStereochemistryPurine analogueBiochemistryPurineCell cycleProtein kinase AEnzymeCell

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Publication Info

Year: 2002
Type: article
Volume: 9
Issue: 10
Pages: 745-749
Citations: 212
Access: Closed

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APA Style

                            
                                
                                    Thomas G. Davies, 
                                
                                    Johanne Bentley, 
                                
                                    Christine E. Arris
                                
                                et al.
                            
                            (2002). 
                            Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor. 
                            Nature Structural Biology
                            , 9
                            (10)
                            , 745-749.
                            https://doi.org/10.1038/nsb842
                        

Identifiers

DOI: 10.1038/nsb842