TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis

Daniele V. F. Tauriello; Sergio Palomo‐Ponce; Diana Stork; Antonio Berenguer; Jordi Badia-Ramentol; Mar Iglesias; Marta Sevillano; Sales Ibiza; Adrià Cañellas‐Socias; Xavier Hernando‐Momblona; Daniel Byrom; Joan A. Matarin; Alexandre Calon; Elisa Rivas; Ángel R. Nebreda; Antoni Riéra; Camille Stephan‐Otto Attolini; Eduard Batlle

doi:10.1038/nature25492

Keywords

Colorectal cancerCancer researchTumor microenvironmentMetastasisImmunotherapyImmune systemCytotoxic T cellStromal cellBiologyTumour heterogeneityImmune checkpointMedicineCancerImmunologyInternal medicine

MeSH Terms

AllelesAnimalsCell DifferentiationColonic NeoplasmsDisease ModelsAnimalDrug SynergismFemaleHumansImmune EvasionImmunotherapyIntestinal MucosaIntestinesLiver NeoplasmsMaleMiceMutationNeoplasm MetastasisProgrammed Cell Death 1 ReceptorStem CellsT-LymphocytesCytotoxicTh1 CellsTransforming Growth Factor betaTumor Microenvironment

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Publication Info

Year: 2018
Type: article
Volume: 554
Issue: 7693
Pages: 538-543
Citations: 1687
Access: Closed

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APA Style

                            
                                
                                    Daniele V. F. Tauriello, 
                                
                                    Sergio Palomo‐Ponce, 
                                
                                    Diana Stork
                                
                                et al.
                            
                            (2018). 
                            TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis. 
                            Nature
                            , 554
                            (7693)
                            , 538-543.
                            https://doi.org/10.1038/nature25492
                        

Identifiers

DOI: 10.1038/nature25492
PMID: 29443964

Data Quality

Data completeness: 68%