TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

Abstract

Exhausted CD8 T (Tex) cells are a distinct cell lineage that arise during chronic infections and cancers in animal models and humans. Tex cells are characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression, ...Read More

Keywords

BiologyEffectorLymphokineCD8SecretionLineage (genetic)ImmunologyCell biologyReceptorImmune systemGeneticsEndocrinologyGene

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Publication Info

Year: 1989
Type: review
Volume: 7
Issue: 1
Pages: 145-173
Citations: 7559
Access: Closed

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APA Style

                            
                                    Tim R. Mosmann, 
                                
                                    Robert L. Coffman
                                
                            (1989). 
                            TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties. 
                            Annual Review of Immunology
                            , 7
                            (1)
                            , 145-173.
                            https://doi.org/10.1146/annurev.iy.07.040189.001045

Identifiers

DOI: 10.1146/annurev.iy.07.040189.001045