The antiphospholipid syndrome is an autoimmune disorder of hypercoagulability characterized by the presence of autoantibodies to various phospholipids or phospholipid-binding proteins. The autoantibodies include anticardiolipin antibodies, lupus anticoagulant antibodies, and antibodies to β2-glycoprotein I (a phospholipid-binding protein). These autoantibodies have both procoagulant and anticoagulant effects, but the procoagulant effects predominate, resulting in syndromes of venous and arterial thrombosis and pregnancy loss.
<i>Background:</i> Anticardiolipin (aCl) and anti-β<sub>2</sub>-glycoprotein I (anti-β<sub>2</sub>-gpI) antibodies are autoantibodies associa...
Study objectives were to determine, in children with systemic lupus erythematosus (SLE), (1) the association of antiphosholipid antibody (APLA) subtypes with thrombotic events (...
Abstract: The association of antiphospholipid antibodies (APA) has been reported in several cases of patients with non‐Hodgkin's lymphoma (NHL) with or without thromboembolic co...
The aim of this study was to determine if the measurement of anti-β2-glycoprotein I antibodies (aβ2-GPI) in serum levels contributes to the better characterization of the clinic...
Summary Asymptomatic antiphospholipid antibody (aPL) carriers with high risk for thrombosis may benefit from preventive anticoagulation. It was our objective to test whether the...
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