Abstract
Complete DNA methylomes for several organisms are now available, helping clarify the evolutionary story of this epigenetic mark and its distribution in key genomic elements. Nonetheless, a complete understanding of its role, the mechanisms responsible for its establishment and maintenance, and its cross talk with other components of cellular machinery remains elusive.
Keywords
EpigeneticsDNA methylationBiologyEpigenomicsGeneticsGenomeComputational biologyGeneGene expression
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Publication Info
- Year
- 2010
- Type
- review
- Volume
- 585
- Issue
- 13
- Pages
- 1994-2000
- Citations
- 94
- Access
- Closed
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Cite This
Mattia Pelizzola,
Joseph R. Ecker
(2010).
The DNA methylome.
FEBS Letters
, 585
(13)
, 1994-2000.
https://doi.org/10.1016/j.febslet.2010.10.061
Identifiers
- DOI
- 10.1016/j.febslet.2010.10.061