The Effect of Advances in Lung-Cancer Treatment on Population Mortality

Abstract

Population-level mortality from NSCLC in the United States fell sharply from 2013 to 2016, and survival after diagnosis improved substantially. Our analysis suggests that a reduction in incidence along with treatment advances - particularly approvals for and use of targeted therapies - is likely to explain the reduction in mortality observed during this period.

Keywords

MedicineLung cancerIncidence (geometry)PopulationEpidemiologyCancerRelative survivalInternal medicineOncologyMortality rateDemographyCancer registryEnvironmental health

MeSH Terms

CarcinomaNon-Small-Cell LungFemaleHumansIncidenceLung NeoplasmsMaleMortalitySEER ProgramSex FactorsUnited States

Affiliated Institutions

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Publication Info

Year: 2020
Type: article
Volume: 383
Issue: 7
Pages: 640-649
Citations: 1606
Access: Closed

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APA Style

                            
                                
                                    Nadia Howlader, 
                                
                                    Gonçalo Forjaz, 
                                
                                    Meghan J. Mooradian
                                
                                et al.
                            
                            (2020). 
                            The Effect of Advances in Lung-Cancer Treatment on Population Mortality. 
                            New England Journal of Medicine
                            , 383
                            (7)
                            , 640-649.
                            https://doi.org/10.1056/nejmoa1916623
                        

Identifiers

DOI: 10.1056/nejmoa1916623
PMID: 32786189
PMCID: PMC8577315

Data Quality

Data completeness: 90%