Abstract
Silver ions inhibited the oxidation of glucose, glycerol, fumarate, succinate, D- and L-lactate, and endogenous substrates by intact cell suspensions of Escherichia coli. Silver ions reacted with the respiratory chain at two levels. The site most sensitive to inhibition was located between the b-cytochromes and cytochrome a 2 . The second level of inhibition was in the NADH and succinate dehydrogenase regions of the respiratory chain, and was situated on the substrate side of the flavin components.
Keywords
Respiratory chainEscherichia coliFlavin groupSuccinate dehydrogenaseBiochemistrySubstrate (aquarium)NADH dehydrogenaseDehydrogenaseChemistryGlycerolBiologyEnzyme
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Publication Info
- Year
- 1974
- Type
- article
- Volume
- 20
- Issue
- 6
- Pages
- 883-889
- Citations
- 467
- Access
- Closed
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Cite This
Philip D. Bragg,
D. J. Rainnie
(1974).
The effect of silver ions on the respiratory chain of <i>Escherichia coli</i>.
Canadian Journal of Microbiology
, 20
(6)
, 883-889.
https://doi.org/10.1139/m74-135
Identifiers
- DOI
- 10.1139/m74-135