Abstract
The identification of the genetic basis of complex human diseases such as schizophrenia and diabetes has proven difficult. In their Perspective, Risch and Merikangas propose that we can best accomplish this goal by combining the power of the human genome project with association studies, a method for determining the basis of a genetic disease.
Keywords
Identification (biology)Perspective (graphical)Genome-wide association studyBasis (linear algebra)Computational biologyGenetic associationHuman genomeHuman diseaseSchizophrenia (object-oriented programming)DiseaseComplex diseaseBiologyComputer scienceGeneticsGenomeArtificial intelligenceMedicineGenotypeMathematicsGeneSingle-nucleotide polymorphism
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Publication Info
- Year
- 1996
- Type
- article
- Volume
- 273
- Issue
- 5281
- Pages
- 1516-1517
- Citations
- 5345
- Access
- Closed
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Cite This
Neil Risch,
Kathleen R. Merikangas
(1996).
The Future of Genetic Studies of Complex Human Diseases.
Science
, 273
(5281)
, 1516-1517.
https://doi.org/10.1126/science.273.5281.1516
Identifiers
- DOI
- 10.1126/science.273.5281.1516