Keywords
HMG-CoA reductaseReductaseCholesterolLDL receptorChemistryHomeostasisReceptorCell biologyBiochemistryBiologyLipoproteinEnzyme
Affiliated Institutions
Related Publications
Once‐daily pravastatin in patients with primary hypercholesterolemia: A dose‐response study
Abstract This multicenter, double‐blind, placebo‐controlled study was conducted to evaluate dose‐response effects and safety of once‐daily administration of pravastatin, a new i...
Comparison of Once-Daily, niacin Extended-Release/lovastatin with standard doses of atorvastatin and simvastatin (the advicor versus other Cholesterol-Modulating agents trial evaluation [ADVOCATE])
This study compared the relative efficacy of a once-daily niacin extended-release (ER)/lovastatin fixed-dose combination with standard doses of atorvastatin or simvastatin, with...
Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR**STELLAR = Statin Therapies for Elevated Lipid Levels compared Across doses to Rosuvastatin. Trial)
The primary objective of this 6-week, parallel-group, open-label, randomized, multicenter trial was to compare rosuvastatin with atorvastatin, pravastatin, and simvastatin acros...
Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins.
Human low density lipoprotein (LDL) was incubated with an established line of rabbit aortic endothelial cells. Density gradient fractionation showed a time-, concentration-, and...
A macrophage receptor that recognizes oxidized low density lipoprotein but not acetylated low density lipoprotein
The formation of cholesterol-loaded macrophage foam cells in arterial tissue may occur by the uptake of modified lipoproteins via the scavenger receptor pathway. The macrophage ...
Publication Info
- Year
- 1985
- Type
- article
- Volume
- 26
- Pages
- 3-15
- Citations
- 37
- Access
- Closed
External Links
Social Impact
Altmetric
PlumX Metrics
Social media, news, blog, policy document mentions
Citation Metrics
37
OpenAlex
Cite This
Michael S. Brown,
Joseph L. Goldstein
(1985).
The LDL Receptor and HMG-CoA Reductase — Two Membrane Molecules That Regulate Cholesterol Homeostasis.
Current topics in cellular regulation
, 26
, 3-15.
https://doi.org/10.1016/b978-0-12-152826-3.50008-5
Identifiers
- DOI
- 10.1016/b978-0-12-152826-3.50008-5