Abstract
Patients with frontotemporal dementia (FTD) with no known diagnosis of ALS or family history of ALS were clinically and electrophysiologically assessed for the presence of ALS. Of 36 patients studied, five met criteria for a definite diagnosis of ALS and two had EMG findings suggestive of denervation in one limb. An additional five patients had prominent fasciculations and six other patients had trouble swallowing but all had normal results on EMG studies. One of the patients with fasciculations and a normal EMG study progressed to definite ALS over the course of 1 year.
Keywords
FasciculationAmyotrophic lateral sclerosisFrontotemporal dementiaMedicineDenervationSwallowingC9orf72Physical medicine and rehabilitationDementiaPsychologyAudiologyInternal medicineSurgeryDiseaseAnatomy
MeSH Terms
AdultAgedAged80 and overAmyotrophic Lateral SclerosisCross-Sectional StudiesDementiaDiagnosisDifferentialFemaleHumansMaleMiddle Aged
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Publication Info
- Year
- 2002
- Type
- article
- Volume
- 59
- Issue
- 7
- Pages
- 1077-1079
- Citations
- 696
- Access
- Closed
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Cite This
Catherine Lomen‐Hoerth,
Thomas Anderson,
Bruce L. Miller
(2002).
The overlap of amyotrophic lateral sclerosis and frontotemporal dementia.
Neurology
, 59
(7)
, 1077-1079.
https://doi.org/10.1212/wnl.59.7.1077
Identifiers
- DOI
- 10.1212/wnl.59.7.1077
- PMID
- 12370467