Abstract

Pfam is a large collection of protein families and domains. Over the past 2 years the number of families in Pfam has doubled and now stands at 6190 (version 10.0). Methodology improvements for searching the Pfam collection locally as well as via the web are described. Other recent innovations include modelling of discontinuous domains allowing Pfam domain definitions to be closer to those found in structure databases. Pfam is available on the web in the UK (http://www.sanger.ac.uk/Software/Pfam/), the USA (http://pfam.wustl.edu/), France (http://pfam.jouy.inra.fr/) and Sweden (http://Pfam.cgb.ki.se/).

Keywords

BiologyComputational biologyDatabaseProtein domainGeneticsComputer science

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Publication Info

Year
2003
Type
article
Volume
32
Issue
90001
Pages
138D-141
Citations
3121
Access
Closed

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Alex Bateman (2003). The Pfam protein families database. Nucleic Acids Research , 32 (90001) , 138D-141. https://doi.org/10.1093/nar/gkh121

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DOI
10.1093/nar/gkh121