The ProDom database of protein domain families: more emphasis on 3D

Abstract

ProDom is a comprehensive database of protein domain families generated from the global comparison of all available protein sequences. Recent improvements include the use of three-dimensional (3D) information from the SCOP database; a completely redesigned web interface (http://www.toulouse.inra.fr/prodom.html); visualization of ProDom domains on 3D structures; coupling of ProDom analysis with the Geno3D homology modelling server; Bayesian inference of evolutionary scenarios for ProDom families. In addition, we have developed ProDom-SG, a ProDom-based server dedicated to the selection of candidate proteins for structural genomics.

Keywords

BiologyStructural genomicsProtein domainInferenceVisualizationDatabaseDomain (mathematical analysis)Web serverInterface (matter)Computational biologyGenomicsSelection (genetic algorithm)Protein structure databaseHomology (biology)BioinformaticsThe InternetGenomeProtein structureComputer scienceGeneticsData miningWorld Wide WebSequence databaseGeneArtificial intelligence

Affiliated Institutions

Centre National de la Recherche Scientifique FR

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Publication Info

Year: 2004
Type: article
Volume: 33
Issue: Database issue
Pages: D212-D215
Citations: 354
Access: Closed

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APA Style

                            
                                    C. Bru
                                
                            (2004). 
                            The ProDom database of protein domain families: more emphasis on 3D. 
                            Nucleic Acids Research
                            , 33
                            (Database issue)
                            , D212-D215.
                            https://doi.org/10.1093/nar/gki034

Identifiers

DOI: 10.1093/nar/gki034