Abstract
Advances in detector technology and image processing are yielding high-resolution electron cryo-microscopy structures of biomolecules. [Also see Report by Amunts et al. ]
Keywords
Affiliated Institutions
Related Publications
Accurate prediction of protein structures and interactions using a three-track neural network
Deep learning takes on protein folding In 1972, Anfinsen won a Nobel prize for demonstrating a connection between a protein’s amino acid sequence and its three-dimensional struc...
Evolutionary-scale prediction of atomic-level protein structure with a language model
Recent advances in machine learning have leveraged evolutionary information in multiple sequence alignments to predict protein structure. We demonstrate direct inference of full...
A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes
Defective Gene Detective Identifying genes that give rise to diseases is one of the major goals of sequencing human genomes. However, putative loss-of-function genes, which are ...
Critical assessment of methods of protein structure prediction (CASP) — round x
ABSTRACT This article is an introduction to the special issue of the journal PROTEINS, dedicated to the tenth Critical Assessment of Structure Prediction (CASP) experiment to as...
Structure of <i>E. coli</i> Glutaminyl-tRNA Synthetase Complexed with tRNA <sup>Gln</sup> and ATP at 2.8 Å Resolution
The crystal structure of Escherichia coli glutaminyl-tRNA synthetase (GlnRS) complexed with its cognate glutaminyl transfer RNA (tRNA Gln ) and adenosine triphosphate (ATP) has ...
Publication Info
- Year
- 2014
- Type
- letter
- Volume
- 343
- Issue
- 6178
- Pages
- 1443-1444
- Citations
- 1286
- Access
- Closed
External Links
Social Impact
Social media, news, blog, policy document mentions
Citation Metrics
Cite This
Identifiers
- DOI
- 10.1126/science.1251652