Thrombolysis in myocardial infarction (TIMI) trial—Phase I: Hemorrhagic manifestations and changes in plasma fibrinogen and the fibrinolytic system in patients treated with recombinant tissue plasminogen activator and streptokinase

Anupama Rao; Craig M. Pratt; Andrew Berke; Allan S. Jaffe; Ira S. Ockene; Theodore Schreiber; William R. Bell; Genell L. Knatterud; Thomas Robertson; Michael L. Terrin

doi:10.1016/0735-1097(88)90158-1

Keywords

StreptokinaseMedicineMyocardial infarctionFibrinogenFibrinThrombolysisTIMITissue plasminogen activatorInternal medicinePlasminogen activatorBatroxobinAprotininFibrinolysisT-plasminogen activatorCardiologyPlasminAnesthesiaImmunology

Affiliated Institutions

National Institutes of Health US

Related Publications

Influence of time to treatment on early infarct-related artery patency after different thrombolytic regimens

Uwe Zeymer , Ulrich Tebbe , R. von Essen +2 more

1999 American Heart Journal 68 citations

Efficacy of Intra-Arterial Fibrinolysis for Acute Ischemic Stroke

Meng Lee , Keun‐Sik Hong , Jeffrey L. Saver

Background and Purpose— Although intra-arterial (IA) fibrinolysis for acute ischemic stroke has been clinically available for many years, it is not a therapy approved by the US ...

2010 Stroke 154 citations

Hemorrhagic Transformation Within 36 Hours of a Cerebral Infarct

Marco Fiorelli , Stefano Bastianello , Rüdiger von Kummer +7 more

Background and Purpose —The clinical correlates of the varying degrees of early hemorrhagic transformation of a cerebral infarct are unclear. We investigated the cohort of a ran...

1999 Stroke 729 citations

Coronary thrombolysis--clinical guidelines and public policy: results of an Ontario practitioner survey.

C. David Naylor , A.Andrew Hollenberg , Anne‐Marie Ugnat +1 more

The Ontario Medical Association (OMA) guidelines for intravenous thrombolysis in acute myocardial infarction were released in March 1988 and contributed to a government decision...

1990 PubMed 14 citations

The rtPA (Alteplase) 0- to 6-Hour Acute Stroke Trial, Part A (A0276g)

Wayne M. Clark , Gregory W. Albers , Kenneth P. Madden +1 more

Background and Purpose —The Thrombolytic Therapy in Acute Ischemic Stroke Study, which started in August of 1991, was designed to assess the efficacy and safety of intravenous r...

2000 Stroke 415 citations

Publication Info

Year: 1988
Type: article
Volume: 11
Issue: 1
Pages: 1-11
Citations: 985
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Thrombolysis in myocardial infarction (TIMI) trial—Phase I: Hemorrhagic manifestations and changes in plasma fibrinogen and the fibrinolytic system in patients treated with recombinant tissue plasminogen activator and streptokinase

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

985

OpenAlex

Cite This

APA Style

                            
                                
                                    Anupama Rao, 
                                
                                    Craig M. Pratt, 
                                
                                    Andrew Berke
                                
                                et al.
                            
                            (1988). 
                            Thrombolysis in myocardial infarction (TIMI) trial—Phase I: Hemorrhagic manifestations and changes in plasma fibrinogen and the fibrinolytic system in patients treated with recombinant tissue plasminogen activator and streptokinase. 
                            Journal of the American College of Cardiology
                            , 11
                            (1)
                            , 1-11.
                            https://doi.org/10.1016/0735-1097(88)90158-1
                        

Identifiers

DOI: 10.1016/0735-1097(88)90158-1