Thymoquinone-loaded nanostructured lipid carriers: preparation, gastroprotection, in vitro toxicity, and pharmacokinetic properties after extravascular administration

Siddig İbrahim Abdelwahab; Manal Mohamed Elhassan Taha; Sheikh .; Chee Wun How; El-Sunousi; Abdullah; Eltayeb E. M. Eid; Umar Yagoub

doi:10.2147/ijn.s44108

Abstract

NLCs could be a promising vehicle for the oral delivery of TQ and improve its gastroprotective properties.

Keywords

ThymoquinoneChemistryPharmacologyPharmacokineticsZeta potentialChromatographyPolyvinyl alcoholDrug carrierAntioxidantDrug deliveryMaterials scienceBiochemistryNanoparticleMedicineOrganic chemistry

MeSH Terms

AnimalsBenzoquinonesCell LineCell SurvivalDrug CarriersHistocytochemistryHumansMaleNanoparticlesNigella sativaParticle SizeProtective AgentsRabbitsRatsRatsSprague-DawleyStomachStomach Ulcer

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Publication Info

Year: 2013
Type: article
Volume: 8
Pages: 2163-2163
Citations: 121
Access: Closed

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APA Style

                            
                                    Siddig İbrahim Abdelwahab, 
                                
                                    Manal Mohamed Elhassan Taha, 
                                
                                    Sheikh .
                                
                                et al.
                            
                            (2013). 
                            Thymoquinone-loaded nanostructured lipid carriers: preparation, gastroprotection, in vitro toxicity, and pharmacokinetic properties after extravascular administration. 
                            International Journal of Nanomedicine
                            , 8
                            
                            , 2163-2163.
                            https://doi.org/10.2147/ijn.s44108

Identifiers

DOI: 10.2147/ijn.s44108
PMID: 23818776
PMCID: PMC3692342

Data Quality

Data completeness: 90%