Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes

Abstract

In patients who have an acute coronary syndrome with or without ST-segment elevation, treatment with ticagrelor as compared with clopidogrel significantly reduced the rate of death from vascular causes, myocardial infarction, or stroke without an increase in the rate of overall major bleeding but with an increase in the rate of non-procedure-related bleeding. (ClinicalTrials.gov number, NCT00391872.)

Keywords

Affiliated Institutions

• Brigham and Women's Hospital US
• Université Paris Cité FR
• Assistance Publique – Hôpitaux de Paris FR
• Clinical Research Institute US
• University Hospital Heidelberg DE
• Inserm FR
• AstraZeneca (Sweden) SE
• Thrombolysis in Myocardial Infarction Study Group US
• Aarhus University Hospital DK
• Heidelberg University DE
• University of Sheffield GB
• Grochowski Hospital PL
• Wilmington University US

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