Time-gated biological imaging by use of colloidal quantum dots

Abstract

The long (but not too long) fluorescence lifetime of CdSe semiconductor quantum dots was exploited to enhance fluorescence biological imaging contrast and sensitivity by time-gated detection. Significant and selective reduction of the autofluorescence contribution to the overall image was achieved, and enhancement of the signal-to-background ratio by more than an order of magnitude was demonstrated.

Keywords

Quantum dotAutofluorescenceOpticsFluorescenceMaterials scienceBiological imagingFluorescence-lifetime imaging microscopyOptoelectronicsSemiconductorPhysics

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Publication Info

Year: 2001
Type: article
Volume: 26
Issue: 11
Pages: 825-825
Citations: 333
Access: Closed

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APA Style

                            
                                
                                    Maxime Dahan, 
                                
                                    Ted A. Laurence, 
                                
                                    Fabien Pinaud
                                
                                et al.
                            
                            (2001). 
                            Time-gated biological imaging by use of colloidal quantum dots. 
                            Optics Letters
                            , 26
                            (11)
                            , 825-825.
                            https://doi.org/10.1364/ol.26.000825
                        

Identifiers

DOI: 10.1364/ol.26.000825
PMID: 18040463

Data Quality

Data completeness: 77%