Tissue-based map of the human proteome

Abstract

Protein expression across human tissues Sequencing the human genome gave new insights into human biology and disease. However, the ultimate goal is to understand the dynamic expression of each of the approximately 20,000 protein-coding genes and the function of each protein. Uhlén et al. now present a map of protein expression across 32 human tissues. They not only measured expression at an RNA level, but also used antibody profiling to precisely localize the corresponding proteins. An interactive website allows exploration of expression patterns across the human body. Science , this issue 10.1126/science.1260419

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Affiliated Institutions

• Technical University of Denmark DK
• Science for Life Laboratory SE
• Uppsala University SE
• Novo Nordisk Foundation DK
• TU Dortmund University DE
• Chalmers University of Technology SE
• Leibniz Research Centre for Working Environment and Human Factors DE
• Stockholm University SE
• Karolinska Institutet SE
• KTH Royal Institute of Technology SE

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