Keywords
Affiliated Institutions
Related Publications
Inflammatory bowel disease: cause and immunobiology
Crohn's disease and ulcerative colitis are idiopathic inflammatory bowel disorders. In this paper, we discuss how environmental factors (eg, geography, cigarette smoking, sanita...
Toll-Like Receptors
The innate immune system in drosophila and mammals senses the invasion of microorganisms using the family of Toll receptors, stimulation of which initiates a range of host defen...
A family of human receptors structurally related to <i>Drosophila</i> Toll
The discovery of sequence homology between the cytoplasmic domains of Drosophila Toll and human interleukin 1 receptors has sown the conviction that both molecules trigger relat...
The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens
Macrophages orchestrate innate immunity by phagocytosing pathogens and coordinating inflammatory responses. Effective defence requires the host to discriminate between different...
Pathogen Recognition by the Innate Immune System
Microbial infection initiates complex interactions between the pathogen and the host. Pathogens express several signature molecules, known as pathogen-associated molecular patte...
Publication Info
- Year
- 2001
- Type
- review
- Volume
- 1
- Issue
- 2
- Pages
- 135-145
- Citations
- 4198
- Access
- Closed
External Links
Social Impact
Social media, news, blog, policy document mentions
Citation Metrics
Cite This
Identifiers
- DOI
- 10.1038/35100529