Abstract

The number of microvessels per 200x field in the areas of most intensive neovascularization in an invasive breast carcinoma may be an independent predictor of metastatic disease either in axillary lymph nodes or at distant sites (or both). Assessment of tumor angiogenesis may therefore prove valuable in selecting patients with early breast carcinoma for aggressive therapy.

Keywords

AngiogenesisMedicineMetastasisBreast carcinomaPathologyCarcinomaBreast tumorNeovascularizationBreast cancerOncologyCancer researchInternal medicineCancer

MeSH Terms

AdultAgedAged80 and overBreast NeoplasmsCarcinomaIntraductalNoninfiltratingHumansLymph NodesLymphatic MetastasisMicrocirculationMiddle AgedNeoplasm InvasivenessNeoplasm MetastasisNeovascularizationPathologicPrognosisRegression Analysis

Affiliated Institutions

Related Publications

Publication Info

Year
1991
Type
article
Volume
324
Issue
1
Pages
1-8
Citations
5648
Access
Closed

Social Impact

Social media, news, blog, policy document mentions

Citation Metrics

5648
OpenAlex
150
Influential
4284
CrossRef

Cite This

Noel Weidner, Joseph P. Semple, William R. Welch et al. (1991). Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma. New England Journal of Medicine , 324 (1) , 1-8. https://doi.org/10.1056/nejm199101033240101

Identifiers

DOI
10.1056/nejm199101033240101
PMID
1701519

Data Quality

Data completeness: 86%