Twenty-Five-Year Follow-up of a Randomized Trial Comparing Radical Mastectomy, Total Mastectomy, and Total Mastectomy Followed by Irradiation

Abstract

The findings validate earlier results showing no advantage from radical mastectomy. Although differences of a few percentage points cannot be excluded, the findings fail to show a significant survival advantage from removing occult positive nodes at the time of initial surgery or from radiation therapy.

Keywords

MedicineMastectomyRadical mastectomyRandomized controlled trialRadiation therapyTotal MastectomyBreast cancerSurgeryModified Radical MastectomyGeneral surgeryCancerInternal medicine

MeSH Terms

Breast NeoplasmsCombined Modality TherapyDisease-Free SurvivalFemaleFollow-Up StudiesHumansIncidenceLymphatic MetastasisMastectomyRadicalMastectomySimpleNeoplasm RecurrenceLocalRandomized Controlled Trials as TopicSurvival Analysis

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Publication Info

Year: 2002
Type: article
Volume: 347
Issue: 8
Pages: 567-575
Citations: 1361
Access: Closed

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APA Style

                            
                                
                                    Bernard Fisher, 
                                
                                    Jong‐Hyeon Jeong, 
                                
                                    Stewart Anderson
                                
                                et al.
                            
                            (2002). 
                            Twenty-Five-Year Follow-up of a Randomized Trial Comparing Radical Mastectomy, Total Mastectomy, and Total Mastectomy Followed by Irradiation. 
                            New England Journal of Medicine
                            , 347
                            (8)
                            , 567-575.
                            https://doi.org/10.1056/nejmoa020128
                        

Identifiers

DOI: 10.1056/nejmoa020128
PMID: 12192016

Data Quality

Data completeness: 86%