Abstract

NCBI RefSeq genome collection http://www.ncbi.nlm.nih.gov/genome represents all three major domains of life: Eukarya, Bacteria and Archaea as well as Viruses. Prokaryotic genome sequences are the most rapidly growing part of the collection. During the year of 2014 more than 10,000 microbial genome assemblies have been publicly released bringing the total number of prokaryotic genomes close to 30,000. We continue to improve the quality and usability of the microbial genome resources by providing easy access to the data and the results of the pre-computed analysis, and improving analysis and visualization tools. A number of improvements have been incorporated into the Prokaryotic Genome Annotation Pipeline. Several new features have been added to RefSeq prokaryotic genomes data processing pipeline including the calculation of genome groups (clades) and the optimization of protein clusters generation using pan-genome approach.

Keywords

RefSeqGenomeBiologyComputational biologyArchaeaEnsemblGenome projectGeneticsGeneGenomics

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Publication Info

Year
2014
Type
article
Volume
43
Issue
D1
Pages
D599-D605
Citations
126
Access
Closed

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Cite This

Tatiana Tatusova, Stacy Ciufo, Scott Federhen et al. (2014). Update on RefSeq microbial genomes resources. Nucleic Acids Research , 43 (D1) , D599-D605. https://doi.org/10.1093/nar/gku1062

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DOI
10.1093/nar/gku1062