Abstract
<h3>CLINICAL SCENARIO</h3> A 55-year-old man had his serum cholesterol level measured at a shopping mall 2 months ago. His cholesterol level was elevated and he comes to you, his primary care physician, for advice. He does not smoke, is not obese, and does not have hypertension, diabetes mellitus, or any first-order relatives with premature coronary heart disease (CHD). You repeat his cholesterol test and schedule a follow-up appointment. The test confirms an elevated cholesterol level (7.9 mmol/L [305 mg/dL]), but before deciding on a treatment recommendation, you elect to find out just how big a reduction in the risk of CHD this patient could expect from a cholesterollowering diet or drug therapy. <h3>THE SEARCH</h3> There are a number of cholesterol-lowering trials, and instead of trying to find and review all of the original studies yourself, you use Grateful Med to find a recent overview. On the first subject line you
Keywords
MedicineCholesterolCoronary heart diseaseDiabetes mellitusBlood cholesterolTest (biology)Primary careScheduleDiseaseLdl cholesterolInternal medicineFamily medicineEndocrinology
Affiliated Institutions
Related Publications
Prediction of Coronary Heart Disease Using Risk Factor Categories
Background —The objective of this study was to examine the association of Joint National Committee (JNC-V) blood pressure and National Cholesterol Education Program (NCEP) chole...
Dyslipidemia and Hyperglycemia Predict Coronary Heart Disease Events in Middle-Aged Patients With NIDDM
Patients with NIDDM are at increased risk for coronary heart disease (CHD). However, information on the predictive value of cardiovascular risk factors and the degree of hypergl...
Is Elevated Serum Cholesterol Level a Risk Factor for Coronary Heart Disease in the Elderly?
Since serum cholesterol is a major component in the causal pathway of atherosclerosis, a pathological process that usually progresses with age, we have evaluated reported findin...
Beyond Cholesterol
IT is now well established that hypercholesterolemia is an important cause of coronary heart disease, and clinical intervention studies have demonstrated the therapeutic value o...
The Lipid Research Clinics Coronary Primary Prevention Trial results. II. The relationship of reduction in incidence of coronary heart disease to cholesterol lowering
In the Lipid Research Clinics Coronary Primary Prevention Trial (LRC-CPPT), a 19% lower incidence of coronary heart disease (CHD) in cholestyramine-treated men was accompanied b...
Publication Info
- Year
- 1994
- Type
- article
- Volume
- 272
- Issue
- 17
- Pages
- 1367-1367
- Citations
- 772
- Access
- Closed
External Links
Social Impact
Altmetric
PlumX Metrics
Social media, news, blog, policy document mentions
Citation Metrics
772
OpenAlex
Cite This
Andrew D Oxman
(1994).
Users' Guides to the Medical Literature.
JAMA
, 272
(17)
, 1367-1367.
https://doi.org/10.1001/jama.1994.03520170077040
Identifiers
- DOI
- 10.1001/jama.1994.03520170077040