Using Positron Emission Tomography and Florbetapir F 18 to Image Cortical Amyloid in Patients With Mild Cognitive Impairment or Dementia Due to...

Abstract

The findings of our analysis confirm the ability of florbetapir-PET SUVRs to characterize amyloid levels in clinically probable AD, MCI, and OHC groups using continuous and binary measures of fibrillar Aβ burden. It introduces criteria to determine whether an image is associated with an intermediate-to-high likelihood of pathologic AD or with having any identifiable cortical amyloid level above that seen in low-risk young controls.

Keywords

NeuropathologyPositron emission tomographyDementiaStandardized uptake valueCognitive impairmentPathologyPathologicalAmyloid (mycology)PsychologyInternal medicineMedicineApolipoprotein EAlzheimer's diseaseDiseaseNuclear medicine

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Publication Info

Year: 2011
Type: article
Volume: 68
Issue: 11
Pages: 1404-1404
Citations: 349
Access: Closed

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APA Style

                            
                                
                                    Adam Fleisher, 
                                
                                    Kewei Chen, 
                                
                                    Xiaofen Liu
                                
                                et al.
                            
                            (2011). 
                            Using Positron Emission Tomography and Florbetapir F 18 to Image Cortical Amyloid in Patients With Mild Cognitive Impairment or Dementia Due to Alzheimer Disease. 
                            Archives of Neurology
                            , 68
                            (11)
                            , 1404-1404.
                            https://doi.org/10.1001/archneurol.2011.150
                        

Identifiers

DOI: 10.1001/archneurol.2011.150