Zika Virus Infection in Dexamethasone-immunosuppressed Mice Demonstrating Disseminated Infection with Multi-organ Involvement Including Orchitis...

Abstract

Besides virus dissemination, inflammation of various tissues, especially orchitis, may be potential complications of ZIKV infection with significant implications on disease transmission and male fertility. Interferon treatment should be considered in patients at high risks for ZIKV-associated complications when the potential benefits outweigh the side effects of treatment.

Keywords

OrchitisVirologyZika virusRecombinant DNAImmunologyDexamethasoneMedicineViral infectionBiologyVirusPathologyInternal medicine

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Publication Info

Year: 2016
Type: article
Volume: 14
Pages: 112-122
Citations: 116
Access: Closed

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APA Style

                            
                                    Jasper Fuk‐Woo Chan, 
                                
                                    Jinxia Zhang, 
                                
                                    Chris Chung‐Sing Chan
                                
                                et al.
                            
                            (2016). 
                            Zika Virus Infection in Dexamethasone-immunosuppressed Mice Demonstrating Disseminated Infection with Multi-organ Involvement Including Orchitis Effectively Treated by Recombinant Type I Interferons. 
                            EBioMedicine
                            , 14
                            
                            , 112-122.
                            https://doi.org/10.1016/j.ebiom.2016.11.017

Identifiers

DOI: 10.1016/j.ebiom.2016.11.017